Selected Publications

  1. Piccio LM, Stark JL, Cross AH: Chronic Calorie Restriction Attenuates Experimental Autoimmune Encephalomyelitis. J Leuk Biol 84: 940-948, 2008
  2. Piccio LM, Buonsanti C, Schmidt RE, Rinker J, Panina-Bordignon P, Cella M, Colonna M, Cross AH: Identification of a novel soluble TREM-2 protein in the cerebrospinal fluid in association with central nervous system inflammation. Brain 2008; 131: 3081-3091. PMCID: PMC2577803
  3. Wilson, E.H., Harris, T.H., Mrass, P., John, B., Tait, E.D., Wu, G.F., Pepper, M., Wherry, E.J., Dzierzinkski, F., Roos, D., Haydon, P.G., Laufer, T.M., Weninger, W., Hunter, C.A. Behavior of parasite specific effector CD8+ T cells in the CNS and visualization of a kinesis-associated system of reticular fibers during infection Immunity. 2009 Feb 20; 30 (2): 300-11.
  4. Naismith RT, Piccio L, Lyons JA, Lauber J, Tutlam NT, Parks BJ, Trinkaus K, Song SK, Cross AH: Rituximab add-on therapy for breakthrough relapsing multiple sclerosis: a 52-week phase II trial. Neurology 2010; 74: 1860-1867 PMCID: PMC2882224
  5. Wu GF, Shindler KS, Allenspach EJ, Stephen TL, Thomas HL, Mikesell RJ,Cross AH, Laufer TM. Limited sufficiency of antigen presentation by dendritic cells in models of central nervous system autoimmunity. J Autoimmun 2011; 36:56-64.PMCID: PMC3053076
  6. Wang Y, Wang Q, Haldar JP, Yeh FC, Xie M, Sun P, Trinkaus K, Klein RS,Cross AH, Song S-K. Quantification of increased cellularity during inflammatory demyelination. Brain 2011; 134: 3587-9 PMCID: PMC3235568
  7. Klawiter EC, Xu J, Naismith RT, Benzinger TLS, Shimony JS, Lancia S, Snyder AZ, Trinkaus K, Song SK,Cross AH. Increased radial diffusivity in spinal cord lesions in neuromyelitis optica compared with multiple sclerosis. Mult Scler 2012;18: 1259-68. Doi:10.1177/1352458512436593. PMID: 22354742
  8. Luo J, Jagadeesan B,Cross AH, Yablonskiy DA. Gradient echo plural contrast imaging- signal model and derived contrasts: T2*, T1, Phase, SWI, T1f, FST2* and T2*-SWI. NeuroImage 2012;60:1073-82 PMCID: PMC3303959
  9. Yablonskiy DA, Luo J, Sukstanskii AL, Iyer A,Cross AH. Biophysical mechanisms of MRI signal frequency contrast in multiple sclerosis. Proc Natl Acad Sci USA. 2012; 109:14212-7. doi: 10.1073/pnas.1206037109.
  10. Archambault, A.S., Carrero, J.A., McGee, N.G., Sim, J., Wright, J., Raabe, T., Chen, P., Ding, H., Allenspach, E.J., Dragatsis, I., Laufer, T.M., and Wu, G.F. Conditional MHCII expression reveals a limited role for B cell antigen presentation in primary and secondary CD4 T cell responses. J Immunol. 2013;191:545-50. PMCID: PMC371153
  11. Satake, A., Schmidt, A.M., Archambault, A.S., Wu, G.F. and Kambayashi, T. Differential targeting of IL-2 and T cell receptor signaling pathways selectively expands regulatory T cells while inhibiting conventional T cells. J Autoimmun. 2013;44:13-20. PMCID: PMC3752416
  12. Fenoglio C, Ridolfi E, Cantoni C, de Riz M, Bonsi R, Serpente M, Villa C, Pietroboni AM, Naismith RT, Alvarez E, Bresolin N, Cross AH, Piccio LM, Galimberti D, Scarpini E. Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis Mult Scler. 2013;19:1938-42. (PMCID pending)
  13. Piccio L, Cantoni C, Ramsbottom M, Mikesell B, Cremasco V, Haynes W, Dong LQ, Chan L, Galimberti D, Cross AH. Lack of adiponectin leads to increased lymphocyte activation and worse severity of a mouse model of multiple sclerosis. Eur J Immunol 2013; 43: 2089-2100. PMCID:PMC390153
  14. Naismith RT, Xu J, Klawiter EC, Lancia S, Tutlam NT, Wagner JM, Qian P, Trinkaus K, Song SK, Cross AH. Spinal cord tract diffusion tensor imaging reveals disability substrate in demyelinating disease. Neurology. 2013; 80:2201-9. PMCID:PMC3721096
  15. Shin S, Walz KA, Archambault AS, Sim J, Bollman BP, Koenigsknecht-Talboo J, Cross AH, Holtzman DM, Wu GF. Apolipoprotein E Mediation of Neuro-inflammation in a Murine Model of Multiple Sclerosis. J Neuroimmunol 2014; 271:8-17 PMCID: PMC4042395
  16. Barnett LG1, Simkins HM, Barnett BE, Korn LL, Johnson AL, Wherry EJ, Wu GF, Laufer TM. B cell antigen presentation in the initiation of follicular helper T cell and germinal center differentiation. J Immunol. 2014;192:3607-17. PMID: 24646739 (PMCID pending)
  17. Lin TH, Spees WM, Chiang CW, Trinkaus K, Cross AH,Song, SK. Diffusion fMRI detects white-matter dysfunction in mice with acute optic neuritis. Neurobiol Dis 2014;67:1-8. PMCID: PMC4035476
  18. Cruz-Orengo L, Daniels BP, Dorsey D, Basak SA, Grajales-Reyes JG, McCandless EE, Piccio L, Schmidt RE, Cross AH, Crosby SD, Klein RS. Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility. J Clin Invest, 2014; 124:2571-84. PMCID: PMC4089451
  19. Chiang CW, Wang Y, Sun P, Lin T-S, Trinkaus K, Cross AH, Song S-K. Quantifying white matter tract diffusion parameters in the presence of increased extra-fiber cellularity and vasogenic edema. NeuroImage 2014;101C:310-319. PMCID: PMC4165711
  20. Wen J, Cross AH, Yablonskiy D. On the role of physiological fluctuations in quantitative gradient echo MRI – Implications for GEPCI, QSM and SWI. Magn Res Med 2015; 73:195-203. PMCID: PMC4116475
  21. Wang Y, Sun P, Wang Q, Trinkaus K, Naismith RT, Cross AH, Song SK. Differentiation and quantification of inflammation, demyelination, and axon injury/loss in MS. Brain. 2015;138(Pt 5):1223-38. PMCID pending
  22. Longbrake EE, Cross AH. Dimethyl Fumarate Associated Lymphopenia in Clinical Practice. Mult Scler. 2015;21:796-7. PMCID: PMC4426020
  23. Parker, C.R., Archambault, A.S., Sim, J., Ferris, S.T., Mikesell, R.J., Koni, P.A., Shimoda, M., Linington, C., Russel, J.H., and Wu, G.F. B cell antigen presentation is sufficient to drive neuro-inflammation in an animal model of multiple sclerosis. J Immunol. 2015 Jun 1;194:5077-84.
  24. Wu, G.F., Brier, M.R., Parks, C.A.-L., Ances, B.M., and Van Stavern, G.P. An eye on brain integrity: Acute optic neuritis affects resting state functional connectivity. Invest Ophthalmol Vis Sci. Apr 2015;56:2541–2546.
  25. Cantoni C, Bollman B, Licastro D, Xie M, Mikesell R, Schmidt R, Yuede CM, Galimberti D, Olivecrona G, Klein RS, Cross AH, Otero K, Piccio L. TREM2 regulates microglial cell activation in response to demyelination in vivo. 2015;129:429-47.