Brier Lab
Matthew R. Brier, MD, PhD
Our lab uses magnetic resonance imaging (MRI) and positron emission tomography (PET) to study the pathological drivers of tissue damage and disability in MS. We are interested in understanding how unrecognized or under-treated aspects of MS pathophysiology contribute to symptoms, clinical worsening, and neurodegeneration in patients with MS. Our goal is to further understand how MS exerts its pathological influence on the brain and spine in hopes of identifying novel therapeutic avenues for patients living with MS.
Cross Lab
Anne Cross, MD
The goal of the Cross lab’s research is to understand the mechanisms involved in pathogenesis of inflammation and demyelination in the central nervous system (brain and spinal cord).
Saligrama Lab
Naresha Saligrama, PhD
The focus of the Saligrama lab is on T cell repertoire in autoimmunity, T cell specificity and function in autoimmunity and systems analysis of immune system in neurological disorders.
Wu Lab
Gregory Wu, MD, PhD
The main goal of the Wu lab’s research is to define the antigen presentation requirements during inflammation within the central nervous system (CNS). Several different antigen-presenting cells (APCs) participate in CD4 T cell-mediated immunity.